α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity
Summary: Anomalous aggregation of α-synuclein (α-Syn) is a pathological hallmark of many degenerative synucleinopathies including Lewy body dementia (LBD) and Parkinson’s disease (PD). Despite its strong link to disease, the precise molecular mechanisms that link α-Syn aggregation to neurodegenerati...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Elsevier
2023-10-01
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| Reeks: | Cell Reports |
| Onderwerpen: | |
| Online toegang: | http://www.sciencedirect.com/science/article/pii/S2211124723012561 |
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