pVHL status in clear cell renal cell carcinoma regulates HIF-α and E-cadherin expression levels and their implications for tumor progression

Objectives: This study aimed to determine the effects of von Hippel–Lindau protein (VHL) expression on hypoxia-inducible factor (HIF) and E-cadherin proteins. Furthermore, to evaluate the influence of the VHL–HIF–E-cadherin pathway in clear cell renal cell carcinoma (ccRCC). Materials and Methods: T...

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Autori principali:	Raviprakash T. Sitaram, Börje Ljungberg
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Upsala Medical Society 2025-12-01
Serie:	Upsala Journal of Medical Sciences
Soggetti:	renal cell carcinoma ccrcc e-cadherin hif-1α hif-2α hif-3α emt tumor progression
Accesso online:	https://ujms.net/index.php/ujms/article/view/12982/20535
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