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pVHL status in clear cell renal cell carcinoma regulates HIF-α and E-cadherin expression levels and their implications for tumor progression

Objectives: This study aimed to determine the effects of von Hippel–Lindau protein (VHL) expression on hypoxia-inducible factor (HIF) and E-cadherin proteins. Furthermore, to evaluate the influence of the VHL–HIF–E-cadherin pathway in clear cell renal cell carcinoma (ccRCC). Materials and Methods: T...

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Principais autores: Raviprakash T. Sitaram, Börje Ljungberg
Format: Artigo
Sprog:Inglês
Udgivet: Upsala Medical Society 2025-12-01
Serier:Upsala Journal of Medical Sciences
Fag:
renal cell carcinoma
ccrcc
e-cadherin
hif-1α
hif-2α
hif-3α
emt
tumor progression
Online adgang:https://ujms.net/index.php/ujms/article/view/12982/20535
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