Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models

PFAS are ubiquitous industrial chemicals with known adverse health effects, particularly on the liver. The liver, being a vital metabolic organ, is susceptible to PFAS-induced metabolic dysregulation, leading to conditions such as hepatotoxicity and metabolic disturbances. In this study, we investig...

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Autori principali:	Andi Alijagic, Lisanna Sinisalu, Daniel Duberg, Oleksandr Kotlyar, Nikolai Scherbak, Magnus Engwall, Matej Orešič, Tuulia Hyötyläinen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-08-01
Serie:	Environment International
Soggetti:	HepG2 HepaRG PFAS Lipidomics Metabolomics Bile acids
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0160412024004069
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