Metabolic and phenotypic changes induced by PFAS exposure in two human hepatocyte cell models

PFAS are ubiquitous industrial chemicals with known adverse health effects, particularly on the liver. The liver, being a vital metabolic organ, is susceptible to PFAS-induced metabolic dysregulation, leading to conditions such as hepatotoxicity and metabolic disturbances. In this study, we investig...

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Detalhes bibliográficos

Principais autores:	Andi Alijagic, Lisanna Sinisalu, Daniel Duberg, Oleksandr Kotlyar, Nikolai Scherbak, Magnus Engwall, Matej Orešič, Tuulia Hyötyläinen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-08-01
Colecção:	Environment International
Assuntos:	HepG2 HepaRG PFAS Lipidomics Metabolomics Bile acids
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0160412024004069
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