iPSC-derived reactive astrocytes from patients with multiple sclerosis protect cocultured neurons in inflammatory conditions

Multiple sclerosis (MS) is the most common chronic central nervous system inflammatory disease. Individual courses are highly variable, with complete remission in some patients and relentless progression in others. We generated induced pluripotent stem cells (iPSCs) to investigate possible mechanism...

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Bibliographic Details

Main Authors:	Janis Kerkering, Bakhrom Muinjonov, Kamil S. Rosiewicz, Sebastian Diecke, Charlotte Biese, Juliane Schiweck, Claudia Chien, Dario Zocholl, Thomas Conrad, Friedemann Paul, Marlen Alisch, Volker Siffrin
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 2023-07-01
Series:	The Journal of Clinical Investigation
Subjects:	Inflammation Stem cells
Online Access:	https://doi.org/10.1172/JCI164637
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