Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia

Abstract Aberrant glucose homeostasis is the most common metabolic disturbance affecting one in ten adults worldwide. Prediabetic hyperglycemia due to dysfunctional interactions between different human tissues, including pancreas and liver, constitutes the largest risk factor for the development of...

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Bibliografiske detaljer

Principais autores:	Reza Zandi Shafagh, Sonia Youhanna, Jibbe Keulen, Joanne X. Shen, Nayere Taebnia, Lena C. Preiss, Kathrin Klein, Florian A. Büttner, Mikael Bergqvist, Wouter van derWijngaart, Volker M. Lauschke
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2022-12-01
Serier:	Advanced Science
Fag:	glycemic control microfluidic cell culture microphysiological model organ‐on‐a‐chip tissue interaction
Online adgang:	https://doi.org/10.1002/advs.202203368
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