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Phosphorylation-driven effector switching of Rab7 and Rab12 by the leucine-rich repeat kinase 1 in mast cells

IntroductionMast cells (MCs) mediate immune, allergic, and neuroinflammatory responses by releasing inflammatory mediators upon activation through the immunoglobulin E (IgE) receptor FcεRI or innate stimuli acting through Mas-related G protein coupled receptors (Mrgprs). We previously showed that Ra...

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主要な著者: Jana Omar-Kabha, Sewar Omari, Yaara Gorzalczany, Fatima Amer-Sarsour, Elisabeth Kleeblatt, Mitsunori Fukuda, Avraham Ashkenazi, Ronit Sagi-Eisenberg
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-11-01
シリーズ:Frontiers in Immunology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1709196/full
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