Single-cell RNA sequencing unveils the hidden powers of zebrafish kidney for generating both hematopoiesis and adaptive antiviral immunity

The vertebrate kidneys play two evolutionary conserved roles in waste excretion and osmoregulation. Besides, the kidney of fish is considered as a functional ortholog of mammalian bone marrow that serves as a hematopoietic hub for generating blood cell lineages and immunological responses. However,...

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Autors principals:	Chongbin Hu, Nan Zhang, Yun Hong, Ruxiu Tie, Dongdong Fan, Aifu Lin, Ye Chen, Li-xin Xiang, Jian-zhong Shao
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2024-03-01
Col·lecció:	eLife
Matèries:	single-cell transcriptome profiling zebrafish kidney HSPCs immune cell types hematopoiesis antiviral immunity
Accés en línia:	https://elifesciences.org/articles/92424
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