Leukemia-associated truncation of granulocyte colony-stimulating factor receptor impacts granulopoiesis throughout the life-course

IntroductionThe granulocyte colony-stimulating factor receptor (G-CSFR), encoded by the CSF3R gene, is involved in the production and function of neutrophilic granulocytes. Somatic mutations in CSF3R leading to truncated G-CSFR forms are observed in acute myeloid leukemia (AML), particularly those s...

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Hlavní autoři:	Vilasha Bulleeraz, Michelle Goy, Faiza Basheer, Clifford Liongue, Alister C. Ward
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-01-01
Edice:	Frontiers in Immunology
Témata:	cytokine receptors G-CSFR leukemia neutropenia zebrafish
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1095453/full
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