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Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation

JAK3 is principally activated by members of the interleukin-2 receptor family and plays an essential role in lymphoid development, with inactivating JAK3 mutations causing autosomal-recessive severe combined immunodeficiency (SCID). This study aimed to generate an equivalent zebrafish model of SCID...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Faiza Basheer, Effie Lee, Clifford Liongue, Alister C. Ward
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-10-01
Schriftenreihe:Biomolecules
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Online-Zugang:https://www.mdpi.com/2218-273X/12/10/1521
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