<it>In vitro</it> correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

<p>Abstract</p> <p>Background</p> <p>SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this tech...

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Detalhes bibliográficos

Principais autores:	Bonifazi Emanuela, Nardone Anna, Serafino Annalucia, Bruscia Emanuela, Sangiuolo Federica, Lais Monica, Gruenert Dieter C, Novelli Giuseppe
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2002-09-01
coleção:	BMC Medical Genetics
Assuntos:	gene therapy cystic fibrosis transmembrane conductance regulator (<it>CFTR</it>) gene targeting transmission electron microscopy (TEM) transfection
Acesso em linha:	http://www.biomedcentral.com/1471-2350/3/8
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