<it>In vitro</it> correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

<p>Abstract</p> <p>Background</p> <p>SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this tech...

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Autors principals:	Bonifazi Emanuela, Nardone Anna, Serafino Annalucia, Bruscia Emanuela, Sangiuolo Federica, Lais Monica, Gruenert Dieter C, Novelli Giuseppe
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2002-09-01
Col·lecció:	BMC Medical Genetics
Matèries:	gene therapy cystic fibrosis transmembrane conductance regulator (<it>CFTR</it>) gene targeting transmission electron microscopy (TEM) transfection
Accés en línia:	http://www.biomedcentral.com/1471-2350/3/8
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