ALK2 Receptor Kinase Association with FKBP12.6 Is Structurally Conserved with the ALK2-FKBP12 Complex
The immunophilin FKBP12 is a known inhibitor of type I BMP and TGF-β receptors that competes for binding with their substrate SMADs. FKBP12 and the close paralog FKBP12.6 additionally assemble with ryanodine receptors to control Ca<sup>2+</sup> release. Binding of FKBP12.6 to BMP/TGF-β receptors has...
Salvato in:
| Autori principali: | , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI AG
2021-01-01
|
| Serie: | Biomedicines |
| Soggetti: | |
| Accesso online: | https://www.mdpi.com/2227-9059/9/2/129 |
| Tags: |
Nessun Tag, puoi essere il primo ad aggiungerne!!
|