Multivalent design of the monoclonal SynO2 antibody improves binding strength to soluble α-Synuclein aggregates
Soluble aggregates are reported to be the most neurotoxic species of α-Synuclein (αSyn) in Parkinson’s disease (PD) and hence are a promising target for diagnosis and treatment of PD. However, the predominantly intracellular location of αSyn limits its accessibility, especially for antibody-based mo...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis Group
2023-12-01
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| Seri Bilgileri: | mAbs |
| Konular: | |
| Online Erişim: | https://www.tandfonline.com/doi/10.1080/19420862.2023.2256668 |
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