FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells

The study of peptide repertoires presented by major histocompatibility complex (MHC) molecules and the identification of potential T-cell epitopes contribute to a multitude of immunopeptidome-based treatment approaches. Epitope mapping is essential for the development of promising epitope-based appr...

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Autors principals:	Luisa Weisbrod, Luigi Capriotti, Marco Hofmann, Valerie Spieler, Herbert Dersch, Bernd Voedisch, Peter Schmidt, Susanne Knake
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-05-01
Col·lecció:	Frontiers in Immunology
Matèries:	T-cell epitope mapping HLA antigen-specific autoimmunity artificial antigen-presenting cells immunopeptidomics
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1386160/full
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