Identification of a novel neutralization epitope in rhesus AAVs
Adeno-associated viruses (AAVs) are popular gene therapy delivery vectors, but their application can be limited by anti-vector immunity. Both preexisting neutralizing antibodies (NAbs) and post-administration NAbs can limit transgene expression and reduce the clinical utility of AAVs. The developmen...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2024-12-01
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| Серии: | Molecular Therapy: Methods & Clinical Development |
| Предметы: | |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S2329050124001669 |
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