Identification of a novel neutralization epitope in rhesus AAVs
Adeno-associated viruses (AAVs) are popular gene therapy delivery vectors, but their application can be limited by anti-vector immunity. Both preexisting neutralizing antibodies (NAbs) and post-administration NAbs can limit transgene expression and reduce the clinical utility of AAVs. The developmen...
Gardado en:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2024-12-01
|
| Series: | Molecular Therapy: Methods & Clinical Development |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2329050124001669 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|