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FASTMAP—a flexible and scalable immunopeptidomics pipeline for HLA- and antigen-specific T-cell epitope mapping based on artificial antigen-presenting cells

The study of peptide repertoires presented by major histocompatibility complex (MHC) molecules and the identification of potential T-cell epitopes contribute to a multitude of immunopeptidome-based treatment approaches. Epitope mapping is essential for the development of promising epitope-based appr...

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Wedi'i Gadw mewn:
Prif Awduron: Luisa Weisbrod, Luigi Capriotti, Marco Hofmann, Valerie Spieler, Herbert Dersch, Bernd Voedisch, Peter Schmidt, Susanne Knake
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2024-05-01
Cyfres:Frontiers in Immunology
Pynciau:
T-cell epitope mapping
HLA
antigen-specific
autoimmunity
artificial antigen-presenting cells
immunopeptidomics
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1386160/full
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