Single-cell RNA sequencing reveals the differentiation and regulation of endplate cells in human intervertebral disc degeneration

Abstract Low back pain (LBP) is largely attributed to intervertebral disc degeneration (IVDD), of which the endplate changes are an important component. However, the alterations in cell fate and properties within the endplates during degeneration remain unknown. Here, we firstly performed the single...

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主要な著者:	Chenhao Shi, Yonggang Fan, Xiusheng Huang, Mingzhe Fan, Lantian Zhao, Huafeng Zhang, Shuangfei Ni
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-09-01
シリーズ:	Scientific Reports
主題:	Single-cell RNA sequencing Cartilage endplate Chondrocyte Differentiation Regulation
オンライン･アクセス:	https://doi.org/10.1038/s41598-024-71891-5
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