Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

Macrophages are innate immune cells that adopt diverse activation states in response to their microenvironment. Editing macrophage activation to dampen inflammatory diseases by promoting the repolarization of inflammatory (M1) macrophages to anti-inflammatory (M2) macrophages is of high interest. He...

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Autores principales:	Jan Van den Bossche, Jeroen Baardman, Natasja A. Otto, Saskia van der Velden, Annette E. Neele, Susan M. van den Berg, Rosario Luque-Martin, Hung-Jen Chen, Marieke C.S. Boshuizen, Mohamed Ahmed, Marten A. Hoeksema, Alex F. de Vos, Menno P.J. de Winther
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2016-10-01
Colección:	Cell Reports
Materias:	immunometabolism macrophage polarization macrophage plasticity metabolism inflammation mitochondrial dysfunction M1 M2 polarization alternative macrophage activation macrophage repolarization
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S221112471631213X
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