Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system
Abstract Background Epigenome-edited animal models enable direct demonstration of disease causing epigenetic mutations. Transgenic (TG) mice stably expressing epigenome-editing factors exhibit dramatic and stable changes in target epigenome modifications. Successful germline transmission of a transg...
I tiakina i:
| Ngā kaituhi matua: | , , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
BMC
2022-12-01
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| Rangatū: | Epigenetics & Chromatin |
| Ngā marau: | |
| Urunga tuihono: | https://doi.org/10.1186/s13072-022-00474-3 |
| Ngā Tūtohu: |
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