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Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation

Abstract Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms of HJD in treating drug-induced liver injury (DILI) remain unknown. In this study, a total of 2...

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Principais autores: Yaochen Xie, Shuchen Gong, Lingkun Wang, Zhaoxu Yang, Chen Yang, Guilin Li, Huiyan Zha, Shuying Lv, Boneng Xiao, Xiaoyu Chen, Zhenning Di, Qiaojun He, Jincheng Wang, Qinjie Weng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-06-01
Serier:BMC Complementary Medicine and Therapies
Fag:
Huanglian Jiedu Decoction
Network pharmacology
Drug-induced liver injury
Molecule docking
Tryptophan metabolism
Q-TOF
Online adgang:https://doi.org/10.1186/s12906-024-04517-y
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