Huanglian Jiedu Decoction improves the"central-peripheral"inflammatory microenvironment and enhances the cognitive function of APP/PS1 mice by inhibiting the activation of NLRP3 inflammasome mediated by gut microbiota

Abstract Background Huanglian Jiedu Decoction (HLJDD) is a representative formula for clearing heat and removing toxins, and some basic studies indicated that it can improve the learning cognitive ability of Alzheimer’s disease (AD) mice, but the underlying molecular mechanism of its improvement in...

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Hlavní autoři:	Yani Zhang, Jiahua Wang, Xuetao Li, Ruibo Guo, Liyan Wang, Yang Liu, Yang Yu, Liang Kong
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-08-01
Edice:	Chinese Medicine
Témata:	Huanglian Jiedu Decoction Alzheimer’s disease Gut microbiota NLRP3
On-line přístup:	https://doi.org/10.1186/s13020-025-01180-4
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