Unraveling the treatment effects of huanglian jiedu decoction on drug-induced liver injury based on network pharmacology, molecular docking and experimental validation

Abstract Huanglian Jiedu Decoction (HJD) is a well-known Traditional Chinese Medicine formula that has been used for liver protection in thousands of years. However, the therapeutic effects and mechanisms of HJD in treating drug-induced liver injury (DILI) remain unknown. In this study, a total of 2...

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Hlavní autoři:	Yaochen Xie, Shuchen Gong, Lingkun Wang, Zhaoxu Yang, Chen Yang, Guilin Li, Huiyan Zha, Shuying Lv, Boneng Xiao, Xiaoyu Chen, Zhenning Di, Qiaojun He, Jincheng Wang, Qinjie Weng
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-06-01
Edice:	BMC Complementary Medicine and Therapies
Témata:	Huanglian Jiedu Decoction Network pharmacology Drug-induced liver injury Molecule docking Tryptophan metabolism Q-TOF
On-line přístup:	https://doi.org/10.1186/s12906-024-04517-y
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