Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains

The recently discovered antibiotic teixobactin is produced by uncultured soil bacteria. The antibiotic inhibits cell wall synthesis of Gram-positive bacteria by binding to precursors of cell wall building blocks, and therefore it is thought to be less vulnerable to development of resistance. Teixoba...

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Hlavní autoři:	Kemin Tan, Min Zhou, Robert P. Jedrzejczak, Ruiying Wu, Raul A. Higuera, Dominika Borek, Gyorgy Babnigg, Andrzej Joachimiak
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2020-01-01
Edice:	Current Research in Structural Biology
Témata:	Nonribosomal peptide synthetase Txo1 Txo2 Teixobactin Condensation domain Adenylation domain
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2665928X20300027
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