The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium

Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A. Here we provide evidence for the biosynthesis of rare variants of microcystin that contain a selection of homo-amino acids b...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Tânia Keiko Shishido, Jouni Jokela, Anu Humisto, Suvi Suurnäkki, Matti Wahlsten, Danillo O. Alvarenga, Kaarina Sivonen, David P. Fewer
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2019-05-01
Цуврал:	Marine Drugs
Нөхцлүүд:	adenylation domain hepatotoxin cyanobacteria nonribosomal peptide synthetase (NRPS) polyketide synthase (PKS) mass spectrometry
Онлайн хандалт:	https://www.mdpi.com/1660-3397/17/5/271
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!