A yeast surface display platform for characterizing CAR T cell responses to cancer antigens
Abstract Chimeric antigen receptor (CAR) T cells have become an established immunotherapy with promising results for the treatment of hematological malignancies. However, modulation of the targeted antigen’s surface level in cancer cells affects the quality and safety of CAR-T cell therapy. Here we...
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| Principais autores: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2025-11-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-025-65236-7 |
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