Ulk1(S555) inhibition alters nutrient stress response by prioritizing amino acid metabolism

Metabolic flexibility, the capacity to adapt fuel utilization in response to nutrient availability, is essential for maintaining energy homeostasis and preventing metabolic disease. Here, we investigate the role of Ulk1 phosphorylation at serine 555 (S555), a site regulated by AMPK, in coordinating...

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Bibliografski detalji

Glavni autori:	Orion S. Willoughby, Anna S. Nichenko, Matthew H. Brisendine, Niloufar Amiri, Shelby N. Henry, Daniel S. Braxton, John R. Brown, Braeden J. Kraft, Kalyn S. Jenkins, Adele K. Addington, Alexey V. Zaitsev, Steven T. Burrows, Ryan P. McMillan, Haiyan Zhang, Spencer A. Tye, Charles P. Najt, Siobhan E. Craige, Timothy W. Rhoads, Junco S. Warren, Joshua C. Drake
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-01-01
Serija:	Molecular Metabolism
Teme:	Ulk1 Glucose Amino acids Mitochondria Metabolic flexibility
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2212877825001954
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