Microglial interferon signaling and Aβ plaque pathology are enhanced in female 5xFAD Alzheimer’s disease mice, independent of estrous cycle stage
Abstract Alzheimer’s disease (AD) presents with a sex bias in which women are at higher risk and exhibit more rapid cognitive decline and brain atrophy compared to men. Microglia play a significant role in the pathogenesis and progression of AD and have been shown to be sexually differentiated in he...
Tallennettuna:
| Päätekijät: | , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BMC
2025-12-01
|
| Sarja: | Journal of Neuroinflammation |
| Aiheet: | |
| Linkit: | https://doi.org/10.1186/s12974-025-03659-1 |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|