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Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.

Single nucleotide polymorphisms (SNPs) in MYH9 and APOL1 on chromosome 22 (c22) are powerfully associated with non-diabetic end-stage renal disease (ESRD) in African Americans (AAs). Many AAs diagnosed with type 2 diabetic nephropathy (T2DN) have non-diabetic kidney disease, potentially masking dete...

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Detalles Bibliográficos
Principais autores: Barry I Freedman, Carl D Langefeld, Lingyi Lu, Jasmin Divers, Mary E Comeau, Jeffrey B Kopp, Cheryl A Winkler, George W Nelson, Randall C Johnson, Nicholette D Palmer, Pamela J Hicks, Meredith A Bostrom, Jessica N Cooke, Caitrin W McDonough, Donald W Bowden
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Genetics
Acceso en liña:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002150&type=printable
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