Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans.

Single nucleotide polymorphisms (SNPs) in MYH9 and APOL1 on chromosome 22 (c22) are powerfully associated with non-diabetic end-stage renal disease (ESRD) in African Americans (AAs). Many AAs diagnosed with type 2 diabetic nephropathy (T2DN) have non-diabetic kidney disease, potentially masking dete...

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Hlavní autoři: Barry I Freedman, Carl D Langefeld, Lingyi Lu, Jasmin Divers, Mary E Comeau, Jeffrey B Kopp, Cheryl A Winkler, George W Nelson, Randall C Johnson, Nicholette D Palmer, Pamela J Hicks, Meredith A Bostrom, Jessica N Cooke, Caitrin W McDonough, Donald W Bowden
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2011-06-01
Edice:PLoS Genetics
On-line přístup:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002150&type=printable
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