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Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms of Cell Injury

The Apolipoprotein L1 (APOL1) innate immunity gene product represents the sole member of the APOL gene family in humans capable of secretion into circulation, thereby mediating the trypanolysis of <i>T. brucei brucei</i>. Gain-of-function variants of the APOL1 gene originated and spread among human...

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Principais autores: Razi Khalaila, Karl Skorecki
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-07-01
Series:Cells
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Acceso en liña:https://www.mdpi.com/2073-4409/14/13/1011
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