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Apolipoprotein L1 (APOL1): Consideration of Molecular Evolution, Interaction with APOL3, and Impact of Splice Isoforms Advances Understanding of Cellular and Molecular Mechanisms of Cell Injury

The Apolipoprotein L1 (APOL1) innate immunity gene product represents the sole member of the APOL gene family in humans capable of secretion into circulation, thereby mediating the trypanolysis of <i>T. brucei brucei</i>. Gain-of-function variants of the APOL1 gene originated and spread among human...

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書誌詳細
主要な著者: Razi Khalaila, Karl Skorecki
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2025-07-01
シリーズ:Cells
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/14/13/1011
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