Facile Synthesis of Chrysin-derivatives with Promising Activities as Aromatase Inhibitors
Flavones such as chrysin show structural similarities to androgens, the substrates of human aromatase, which converts androgens to estrogens. Aromatase is a key target in the treatment of hormone-dependent tumors, including breast cancer. Flavone-based aromatase inhibitors are of growing interest, a...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publishing
2011-01-01
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| Series: | Natural Product Communications |
| Online Access: | https://doi.org/10.1177/1934578X1100600108 |
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