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Facile Synthesis of Chrysin-derivatives with Promising Activities as Aromatase Inhibitors

Flavones such as chrysin show structural similarities to androgens, the substrates of human aromatase, which converts androgens to estrogens. Aromatase is a key target in the treatment of hormone-dependent tumors, including breast cancer. Flavone-based aromatase inhibitors are of growing interest, a...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Hamdoon A. Mohammed, Lalla A. Ba, Torsten Burkholz, Elena Schumann, Britta Diesel, Josef Zapp, Alexandra K. Kiemer, Christina Ries, Rolf W. Hartmann, Mohammed Hosny, Claus Jacob
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: SAGE Publishing 2011-01-01
Sarja:Natural Product Communications
Linkit:https://doi.org/10.1177/1934578X1100600108
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