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MICA ∗012:01 Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer

Major histocompatibility complex (HLA) class I chain-related protein A (MICA) regulates immune surveillance through activation of NKG2D (natural killer group 2D) receptor. However, the genetic association, potential function, and predictive ability of MICA alleles with colorectal cancer (CRC) progno...

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Автори: Weifeng Ding, Yanyun Ma, Weifeng Zhu, Weilin Pu, Jianfeng Zhang, Fei Qian, Youlang Zhou, Yan Deng, Shicheng Guo, Jiucun Wang, Xiaodong Zhou
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2020-05-01
Серія:Frontiers in Genetics
Предмети:
MICA polymorphism
colorectal cancer
MICA ∗012:01 allele
immunosurveillance
tumor immunity
Онлайн доступ:https://www.frontiersin.org/article/10.3389/fgene.2020.00511/full
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