High-Throughput MICA/B Genotyping of Over Two Million Samples: Workflow and Allele Frequencies

MICA and MICB are ligands of the NKG2D receptor and thereby influence NK and T cell activity. MICA/B gene polymorphisms, expression levels and the amount of soluble MICA/B in the serum have been linked to autoimmune diseases, infections, and cancer. In hematopoietic stem cell transplantation, MICA m...

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Egile Nagusiak:	Anja Klussmeier, Carolin Massalski, Kathrin Putke, Gesine Schäfer, Jürgen Sauter, Daniel Schefzyk, Jens Pruschke, Jan Hofmann, Daniel Fürst, Raphael Carapito, Seiamak Bahram, Alexander H. Schmidt, Vinzenz Lange
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2020-02-01
Saila:	Frontiers in Immunology
Gaiak:	MICA MICB hematopoietic stem cell transplantation allele genotyping next generation sequencing
Sarrera elektronikoa:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00314/full
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