Major Histocompatibility Complex Class I-Related Chain A (MICA) Allelic Variants Associate With Susceptibility and Prognosis of Gastric Cancer

Gastric cancer (GC) is the fifth most prevalent type of cancer worldwide. Gastric tumor cells express MICA protein, a ligand to NKG2D receptor that triggers natural killer (NK) cells effector functions for early tumor elimination. MICA gene is highly polymorphic, thus originating alleles that encode...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Karen Toledo-Stuardo, Carolina H. Ribeiro, Andrea Canals, Marcela Morales, Valentina Gárate, Jose Rodríguez-Siza, Samantha Tello, Marco Bustamante, Ricardo Armisen, Douglas J. Matthies, Gerald Zapata-Torres, Patricio González-Hormazabal, María Carmen Molina
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2021-03-01
Serie:	Frontiers in Immunology
Ämnen:	gastric cancer MICA gene MICA polymorphism MICA-129 MICA alleles
Länkar:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.645528/full
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!