Transcriptional upregulation of p21/WAF/Cip1 in myeloid leukemic blasts expressing AML1-ETO

An inducible model for conditional expression of AML1-ETO in myeloid U-937 cells was generated previously to determine cellular effects of AML1-ETO and to identify target genes. Induction of AML1-ETO expression in U-937 resulted in reduced cell growth, G1 arrest and apoptosis. Microarray analysis sh...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Tobias Berg, Manfred Fliegauf, Jan Burger, Martin S. Staege, Shaohua Liu, Natalia Martinez, Olaf Heidenreich, Stefan Burdach, Torsten Haferlach, Milton H. Werner, Michael Lübbert
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Ferrata Storti Foundation 2008-11-01
Schriftenreihe:	Haematologica
Online-Zugang:	https://haematologica.org/article/view/5079
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