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The bar-hinge motor: a synthetic protein design exploiting conformational switching to achieve directional motility

One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a peptide-based motor capable of executing directed...

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Principais autores: Lara S R Small, Martin J Zuckermann, Richard B Sessions, Paul M G Curmi, Heiner Linke, Nancy R Forde, Elizabeth H C Bromley
Format: Artigo
Sprog:Inglês
Udgivet: IOP Publishing 2019-01-01
Serier:New Journal of Physics
Fag:
molecular motors
artificial protein motor
langevin dynamics
synthetic biology
nanoscale motion
Online adgang:https://doi.org/10.1088/1367-2630/aaf3ca
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