The bar-hinge motor: a synthetic protein design exploiting conformational switching to achieve directional motility

One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a peptide-based motor capable of executing directed...

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Auteurs principaux:	Lara S R Small, Martin J Zuckermann, Richard B Sessions, Paul M G Curmi, Heiner Linke, Nancy R Forde, Elizabeth H C Bromley
Format:	Artigo
Langue:	Inglês
Publié:	IOP Publishing 2019-01-01
Collection:	New Journal of Physics
Sujets:	molecular motors artificial protein motor langevin dynamics synthetic biology nanoscale motion
Accès en ligne:	https://doi.org/10.1088/1367-2630/aaf3ca
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