The bar-hinge motor: a synthetic protein design exploiting conformational switching to achieve directional motility

One challenge to synthetic biology is to design functional machines from natural building blocks, from individual amino acids up to larger motifs such as the coiled coil. Here we investigate a novel bipedal motor concept, the Bar-Hinge Motor (BHM), a peptide-based motor capable of executing directed...

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Autors principals:	Lara S R Small, Martin J Zuckermann, Richard B Sessions, Paul M G Curmi, Heiner Linke, Nancy R Forde, Elizabeth H C Bromley
Format:	Artigo
Idioma:	Inglês
Publicat:	IOP Publishing 2019-01-01
Col·lecció:	New Journal of Physics
Matèries:	molecular motors artificial protein motor langevin dynamics synthetic biology nanoscale motion
Accés en línia:	https://doi.org/10.1088/1367-2630/aaf3ca
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