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Dual transcriptional activities of PAX3 and PAX7 spatially encode spinal cell fates through distinct gene networks.

Understanding how transcription factors regulate organized cellular diversity in developing tissues remains a major challenge due to their pleiotropic functions. We addressed this by monitoring and genetically modulating the activity of PAX3 and PAX7 during the specification of neural progenitor poo...

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Autors principals: Robin Rondon, Théaud Hezez, Julien Richard Albert, Shinichiro Hayashi, Bernadette Drayton-Libotte, Gloria Gonzalez Curto, Frédéric Auradé, Elie Balloul, Claire Dugast-Darzacq, Frédéric Relaix, Pascale Gilardi-Hebenstreit, Vanessa Ribes
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2025-10-01
Col·lecció:PLoS Biology
Accés en línia:https://doi.org/10.1371/journal.pbio.3003448
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