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A Pax7::Foxo1 conditional mouse strain

Abstract Background The PAX7::FOXO1 subtype of alveolar rhabdomyosarcoma (aRMS) is both understudied and an unmet clinical need. The biology of PAX7::FOXO1 aRMS is significantly different than PAX3::FOXO1 aRMS, presenting an opportunity to gain biological, clinical and therapeutic insights by murine...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: G. Roger Askew, Jonathan Gauntlett, Katherine Brechun, Harald Kranz, Nicholas Salters, Jess D. Tate, Ellen Wang, Cassie Badger, Shireen Elhabian, Jared Schnider, Gillian St. John, Samuel V. Rasmussen, Narendra Bharathy, Charles Keller
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-03-01
Schriftenreihe:Skeletal Muscle
Schlagworte:
Rhabdomyosarcoma
Pax7
Foxo1
Pax3
Pax3:Foxo1
Pax7:Foxo1
Online-Zugang:https://doi.org/10.1186/s13395-026-00424-7
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