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MET promotes hepatocellular carcinoma development through the promotion of TRIB3-mediated FOXO1 degradation

Background/Aims Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, and abnormal MET expression plays a crucial role in its progression. However, the specific pathogenic mechanisms of MET in HCC have yet to be fully elucidated. This study aimed to uncover the oncogenic mechanisms of ME...

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Principais autores: Tiantian Wang, Dean Rao, Chenan Fu, Zhoubin Sun, Yiming Luo, Junli Lu, Jie Jin, Han Li, Feimu Fan, Huifang Liang, Wenjie Huang, Limin Xia
Format: Artigo
Sprog:Inglês
Udgivet: Korean Association for the Study of the Liver 2025-07-01
Serier:Clinical and Molecular Hepatology
Fag:
hepatocellular carcinoma
met
trib3
cop1
foxo1
Online adgang:http://e-cmh.org/upload/pdf/cmh-2024-1163.pdf
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