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Predicting substrates for orphan solute carrier proteins using multi-omics datasets

Abstract Solute carriers (SLC) are integral membrane proteins responsible for transporting a wide variety of metabolites, signaling molecules and drugs across cellular membranes. Despite key roles in metabolism, signaling and pharmacology, around one third of SLC proteins are ‘orphans’ whose substra...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Y. Zhang, S. Newstead, P. Sarkies
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-02-01
Rangatū:BMC Genomics
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12864-025-11330-5
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