Delayed and accelerated aging share common longevity assurance mechanisms.
Mutant dwarf and calorie-restricted mice benefit from healthy aging and unusually long lifespan. In contrast, mouse models for DNA repair-deficient progeroid syndromes age and die prematurely. To identify mechanisms that regulate mammalian longevity, we quantified the parallels between the genome-wi...
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| Główni autorzy: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science (PLoS)
2008-08-01
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| Seria: | PLoS Genetics |
| Dostęp online: | http://europepmc.org/articles/PMC2493043?pdf=render |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
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