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The Study of Alternative Splicing Events in Human Induced Pluripotent Stem Cells From a Down's Syndrome Patient

Down's syndrome (DS) is one of the most commonly known disorders with multiple congenital disabilities. Besides severe cognitive impairment and intellectual disability, individuals with DS also exhibit additional phenotypes of variable penetrance and severity, with one or more comorbid conditions, i...

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Principais autores: Yunjie Wang, Zexu Li, Guanheng Yang, Linlin Cai, Fan Yang, Yaqiong Zhang, Yitao Zeng, Qingwen Ma, Fanyi Zeng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-09-01
Serier:Frontiers in Cell and Developmental Biology
Fag:
Down's syndrome
alternative splicing
iPSCs
gene regulation
differentially expressed genes
Online adgang:https://www.frontiersin.org/articles/10.3389/fcell.2021.661381/full
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