Design, Synthesis and In Vitro Antimicrobial Activity of 6-(1<i>H</i>-Benzimidazol-2-yl)-3,5-dimethyl-4-oxo-2-thio-3,4-dihydrothieno[2,3-<i>d</i>]pyrimidines

The rapid development in bacterial resistance to many groups of known antibiotics forces the researchers to discover antibacterial drug candidates with previously unknown mechanisms of action, one of the most relevant being the inhibition of tRNA (Guanine37-N1)-methyltransferase (TrmD). The discover...

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Manylion Llyfryddiaeth

Prif Awduron:	Sergiy V. Vlasov, Olena D. Vlasova, Hanna I. Severina, Konstantin Yu. Krolenko, Oleksandr V. Borysov, Amjad Ibrahim M. Abu Sharkh, Vitaliy S. Vlasov, Victoriya A. Georgiyants
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2021-11-01
Cyfres:	Scientia Pharmaceutica
Pynciau:	thieno[2,3-<i>d</i>]pyrimidine antimicrobial activity TrmD inhibitor docking study <i>Pseudomonas aeruginosa</i>
Mynediad Ar-lein:	https://www.mdpi.com/2218-0532/89/4/49
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!